GO:0070371 biological_process ERK1 and ERK2 cascade
| PAG Title | GO:0070371 biological_process ERK1 and ERK2 cascade |
| PAG ID | TAX028893 |
| Type | A |
| Source Link |  GOA |
| Publication Reference | NA |
| PAG Description | An intracellular protein kinase cascade containing at least ERK1 or ERK2 (MAPKs), a MEK (a MAPKK) and a MAP3K. The cascade may involve 4 different kinases, as it can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell. |
| Species | Homo sapiens |
| Quality Metric Scores | nCoCo Score: 215 |
| Information Content | Rich |
| Other IDs | GO:0070371 |
| Base PAG ID | TAX028893 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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